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(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

(5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester Featured Image
  • (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester
  • (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester

short description:

Chemical & Physical Properties

Posaconazole intermediate.

Posaconazole, launched in the UK, is the newest member of the azole class of antifungal agents to reach the market. It is indicated for the treatment and prophylaxis of a range of invasive fungal infections, including aspergillosis,fusariosis, chromoblastomycosis, mycetoma, and coccidiomycosis in patients who are refractory to, or intolerant of, standard therapy with amphotericin B and/or itraconazole. In the US, it is approved for the prophylaxis of invasive Aspergillus and Candida infections in patients 13 years of age who are at high risk of developing these infections due to being severely immunocompromised. Additionally, it is approved for the treatment of oropharyngeal candidiasis. Posaconazole has an expanded spectrum of activity over other members of the azole antifungals. In addition to potent activity against refractory cases of aspergillosis and fluconazole-resistant Candida, it demonstrates activity against Zygomycetes.

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Products under patent are offered for R & D purpose only.

  • Appearance : White solid
  • Assay : ≥99.0%
  • Density: 1.4g/cm3
  • Boiling Point: 608.1℃ at 760 mmHg
  • Flash Point: 321.6℃
  • Melting Point: 100-102℃

    • Product Detail

    Product Tags

    Product Description

    Product Name  (5R-cis)-Toluene-4-sulfonic acid 5-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)methyltetrahydrofuran-3-ylmethyl ester CAS 149809-43-8
    Synonyms [(3S,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methyl 4-methylbenzenesulfonate;
     CAS NO  149809-43-8
    Molecular Formula  C21H21F2N3O4S
    Molecular Weight  449.47
    EINECS NO N/A
    MDL NO  MFCD13195567

    Why Choose Us

    1.About price: The price is negotiable. It can be changed according to your quantity or package.
    2. About samples: Samples need sample fee, can do freight collect or you pay us the cost in advance.
    3. About goods: All our goods are made of high-quality environmentally friendly materials.
    4. About MOQ: We can adjust it according to your requirement.
    5. About OEM: You can send your own design and Logo. We can open new mold and logo and then send samples to confirm.
    6. About exchange: Please email me or chat with me at your convenience.
    7. High quality: Using high quality material and establishing a strict quality control system, assigning specific persons in charge of each process of production, from raw material purchase to pack.
    8. Mold workshop, customized model can be made according to the quantity.
    9. We offer the best service as we have. Experienced sales team are already to work for you.
    10. OEM is welcome. Customized logo and color is welcome.
    11. New virgin material used for each product.
    12. How can we guarantee quality?
    Always a pre-production sample before mass production;
    Always 100% Inspection before shipment;
    13. What certification you have?
    We are over 30patents and IATF 16946:2016 Quality Management System Certificate.
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    Accepted Delivery Terms: FOB,CIF,EXW；
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    15. Can you provide OEM & ODM service?
    Yes, OEM&ODM orders are welcome.
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    Warmly welcome to visit our factory!
    17. Are you factory or trading company?
    We are factory and with Export Right. It means factory + trading.
    18. What is your delivery time?
    A: Normally, our delivery time is within 30 days after confirmation.
    19. Can you help to design the packaging artworks?
    Yes, we have professional designer to design all the packaging artworks according to our customer's request.
    20. What are the payment terms?
    We accept T/T (30% as deposit, and 70% against copy of B/L), L/C at sight, other payment terms.
    21. How many days you need for prepare sample and how much?
    10-15days. There is no extra fee for sample and free sample is possible in certain condition.
    22. There are so many suppliers, why choose you as our business partner?
    We focus on auto parts manufacturing for over 15years, most of our customers are brands in North America, that is to say we also have accumulated 15years OEM experience for premium brands.

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