Sitagliptin Phosphate Chemical Compound

Sitagliptin Phosphate Chemical Compound

short description:

Sitagliptin phosphate is dipeptidyl peptidase Ⅳ(DDP-4) inhibitor class of drugs developed by the German Merck company and firstly obtained the US Food and Drug Administration approval for the treatment of type 2 diabetes, is a new antidiabetic drug, can improve the body’s own ability to reduce high blood glucose levels, and the relatively increase naturally occurring incretin by inhibiting the activity of this enzyme, including the levels of glucagon-like peptide 1 and glucose-dependent insulinotropic peptide, thereby triggering the pancreas to improve insulin production and stop glucose production in liver, and ultimately reduce the clinical effect of blood glucose concentration.

  • Appearance : white solid
  • Assay : ≥99.0%
  • Flash Point: 274.3℃
  • Boiling Point: 529.9℃
  • Melting point: 202-204℃
  • Product Detail

    Product Tags

    Product Description

    Product Name  Sitagliptin Phosphate CAS NO654671-78-0
    Synonyms   (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1-butanone phosphate (1:1);
    1-Butanone, 3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (3R)-, phosphate (1:1);
    (3R)-3-amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butan-1-one phosphate (1:1);
    CAS NO  654671-78-0
    Molecular Formula  C16H18F6N5O5P
    Molecular Weight  505.31
    EINECS NO  1806241-263-5
    MDL NO  MFCD22628883

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